BLINDNESS begins in a flash, as one man is instantaneously struck blind while driving home from work, his whole world suddenly turned to an eerie, milky haze. One by one, each person he encounters - his wife, his doctor (Mark Ruffalo), even the seemingly good Samaritan (Don McKellar) who gives him a lift home - will in due course suffer the same unsettling fate. As the contagion spreads, and panic and paranoia set in across the city, the newly blind victims of the "White Sickness" are rounded up and quarantined, while a cure is rapidly explored. But inside the quarantined hospital, there is one secret eyewitness: one woman (Julianne Moore) who pretends she is blind in order to stay beside her beloved husband (Ruffalo). As all semblance of ordinary life in the hospital begins to break down, fuelled by Gael Garcia Bernal's lawless and depraved "King of Ward Three", the doctor's wife is armed with increasing courage and the will to survive. Gathering her makeshift family of seven people, she will guide them on a journey through horror and love, to break out of the hospital and into the devastated city where they may be the only hope left. Their journey shines a light on both the dangerous fragility of society and the exhilarating spirit of humanity.